Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534349 | 0.83 | ACLY (0.53) | HPGDMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7535073 | 0.81 | MAPT (0.55) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7538859 | 0.81 | ACLY (0.53) | MEN1KMT2AACLYNPSR1 | |
| SCHEMBL7534407 | 0.79 | LMNA (0.56) | HPGDMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7537381 | 0.79 | ALDH1A1 (0.53) | HPGDMAPTHSD17B10MEN1KMT2A | |
| SCHEMBL7537030 | 0.78 | MAPT (0.53) | HPGDMAPTNPC1RAB9AMEN1 | |
| SCHEMBL7537204 | 0.78 | MAPT (0.51) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL532975 | 0.78 | ACLY (0.69) | HPGDHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL27180046 | 0.78 | RAB9A (0.72) | HPGDMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL7532668 | 0.78 | LMNA (0.57) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |