Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538001 | 0.90 | ACLY (0.58) | ACLYPTGES2MEN1KMT2ANPC1 | |
| SCHEMBL7533711 | 0.84 | LMNA (0.49) | ACLYMEN1KMT2ATSHRLMNA | |
| SCHEMBL7539012 | 0.82 | LMNA (0.47) | ACLYTSHRLMNAHPGDPOLB | |
| SCHEMBL7537998 | 0.81 | PGR (0.55) | ACLYPTGES2MEN1KMT2APGR | |
| SCHEMBL492007 | 0.81 | ACLY (0.77) | ACLYMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7537343 | 0.80 | S1PR3 (0.47) | ACLYTSHRLMNAHPGDPOLB | |
| Hydrochloric Acid SCHEMBL492324 | 0.80 | ACLY (0.75) | ACLYMEN1KMT2ANPC1RAB9A | |
| SCHEMBL532975 | 0.80 | ACLY (0.69) | ACLYMEN1KMT2ATSHRLMNA | |
| SCHEMBL7533705 | 0.78 | SCN3A (0.56) | ACLYMEN1KMT2ATSHRLMNA | |
| Hydrochloric Acid SCHEMBL533067 | 0.78 | ACLY (0.68) | ACLYMEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |