SCHEMBL753955

SCHEMBL753955

CC(C)(C)c1ccc(S(=O)(=O)CBr)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
LMNA P02545 3/20 0.50
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
RECQL P46063 1/20 0.47
GAA P10253 1/20 0.44
HSD11B1 P28845 1/20 0.44
POLB P06746 1/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
MAPT P10636 3/20 0.43
HPGD P15428 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C19 P33261 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906397 0.83 ALDH1A1 (0.59) ALDH1A1CA1CA2LMNANPC1
SCHEMBL3256579 0.83 ALDH1A1 (0.59) ALDH1A1CA1CA2LMNANPC1
SCHEMBL11451717 0.79 ALDH1A1 (0.55) ALDH1A1CA1CA2LMNANPC1
SCHEMBL14495880 0.79 ALDH1A1 (0.57) ALDH1A1CA1CA2LMNANPC1
SCHEMBL13724875 0.79 MMP1 (0.51) CA1CA2HSD11B1BCHEACHE
SCHEMBL18531400 0.78 ALDH1A1 (0.54) ALDH1A1CA1CA2LMNANPC1
SCHEMBL13761763 0.78 ALDH1A1 (0.53) ALDH1A1CA1CA2LMNANPC1
SCHEMBL12062117 0.76 CA2 (0.56) ALDH1A1CA1CA2LMNANPC1
SCHEMBL10179515 0.76 ALDH1A1 (0.52) ALDH1A1CA1CA2LMNANPC1
SCHEMBL7033893 0.76 ALDH1A1 (0.53) ALDH1A1CA1CA2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US claimed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
US-20100186631-A1 Compounds for preventing ghost odour THOR GMBH (DE) 2010-07-29 US disclosed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone MBTD1, MPST, B2M ALDH1A1 553/4885CA1 3656/4885CA2 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.