Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD1 | O95696 | 1/20 | 0.48 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.48 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678633 | 0.85 | ALDH1A1 (0.60) | SLC22A12ACLYPLA2G7BRD4BRD1 | |
| SCHEMBL6674281 | 0.85 | MAPT (0.61) | SLC22A12PLA2G7MAPTNPSR1ALDH1A1 | |
| SCHEMBL6678890 | 0.81 | LMNA (0.67) | SLC22A12PLA2G7MAPTNPSR1MEN1 | |
| SCHEMBL6677842 | 0.78 | LMNA (0.64) | SLC22A12ACLYPLA2G7MAPTNPSR1 | |
| SCHEMBL6681275 | 0.78 | PLA2G7 (0.56) | SLC22A12PLA2G7MAPTNPSR1MEN1 | |
| SCHEMBL8343255 | 0.77 | SLC22A12 (0.50) | SLC22A12PLA2G7MAPTALDH1A1 | |
| SCHEMBL28047475 | 0.75 | ALDH1A1 (0.63) | MAPTMEN1HTTKMT2ACES1 | |
| SCHEMBL4195364 | 0.74 | EPAS1 (0.51) | SLC22A12ACLYMAPTALDH1A1LMNA | |
| SCHEMBL15867027 | 0.73 | VCAM1 (0.53) | SLC22A12ACLYPLA2G7MEN1CYP3A4 | |
| SCHEMBL6675727 | 0.72 | ALDH1A1 (0.57) | SLC22A12ACLYMAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | AMGEN INC. | 2002-01-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | CYP46A1, TGFB1, NR1H2 | SLC22A12 3172/4885ACLY 2752/4885PLA2G7 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.