Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540486 | 0.73 | SLC27A1 (0.33) | MAPTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL1439724 | 0.58 | CA12 (0.63) | MTNR1AMAPTALDH1A1LMNATAAR1 | |
| Urea SCHEMBL28195209 | 0.57 | CA12 (0.61) | MTNR1AMAPTALDH1A1LMNATAAR1 | |
| SCHEMBL34467344 | 0.55 | ADORA1 (0.42) | MAPTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL5815988 | 0.55 | BTK (0.46) | BTKMAPTALDH1A1LMNAPDE10A | |
| SCHEMBL1444688 | 0.55 | CYP2A6 (0.51) | MTNR1AMEN1KMT2ALMNA | |
| SCHEMBL4967515 | 0.54 | SIRT1 (0.39) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31065216 | 0.54 | MAPK1 (0.33) | MAPTALDH1A1LMNA | |
| SCHEMBL1953254 | 0.53 | L3MBTL1 (0.68) | MAPTALDH1A1KMT2ATAAR1 | |
| SCHEMBL2755853 | 0.53 | MAPK1 (0.60) | MAPTMEN1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |