Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540482 | 0.73 | MTNR1A (0.34) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7545430 | 0.70 | ALOX5 (0.32) | SLC27A1MEN1KMT2A | |
| SCHEMBL7540660 | 0.66 | ALDH1A1 (0.48) | SLC27A1ALDH1A1MAPT | |
| SCHEMBL7536844 | 0.65 | SIRT1 (0.38) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL1842323 | 0.64 | NPC1 (0.52) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7601537 | 0.63 | TGFBR1 (0.35) | SLC27A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1844041 | 0.63 | NPC1 (0.51) | LMNAMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7588936 | 0.60 | KMT2A (0.40) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL11359838 | 0.59 | ALOX15 (0.39) | SLC27A1LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL340272 | 0.58 | ALDH1A1 (0.70) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254123-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Abbott GmbH & Co. KG (DE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001057008-A1 | 2-BENZOTHIAZOLYL UREA DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ABBOTT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG & COMPANY KOMMANDITGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |