Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.40 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539261 | 0.94 | MMP3 (0.47) | MMEACECPA1ACE2CTSL | |
| SCHEMBL7542688 | 0.93 | FOLH1 (0.46) | MMEACECPA1ACE2CTSL | |
| SCHEMBL7538809 | 0.91 | MMP1 (0.47) | CTSLPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7547253 | 0.87 | MME (0.42) | MMEACECPA1ACE2MMP3 | |
| SCHEMBL7543417 | 0.84 | CTSL (0.41) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL7538662 | 0.83 | GRN (0.40) | KMT2ACTSLPSMB11PSMA7PSMB1 | |
| SCHEMBL7541917 | 0.82 | GRN (0.39) | KMT2ACTSLPSMB11PSMA7PSMB1 | |
| SCHEMBL7539424 | 0.82 | KMT2A (0.44) | KMT2ACTSLPSMB11PSMA7PSMB1 | |
| SCHEMBL7539428 | 0.82 | KMT2A (0.44) | KMT2ACTSLPSMB11PSMA7PSMB1 | |
| SCHEMBL7546168 | 0.81 | ITGB1 (0.54) | MMEACECPA1ACE2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |