Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 2/20 | 0.43 |
| ▸ | NPY4R | P50391 | 2/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539261 | 0.94 | MMP3 (0.47) | ACEMMECPA1ACE2CTSL | |
| SCHEMBL7540859 | 0.93 | KMT2A (0.44) | FOLH1ACEMMECPA1ACE2 | |
| SCHEMBL7538809 | 0.92 | MMP1 (0.47) | CTSLMMP3MMP2MMP9MMP8 | |
| SCHEMBL7538620 | 0.87 | FOLH1 (0.45) | FOLH1NPY1RNPY2RNPY4RACE | |
| SCHEMBL7540085 | 0.83 | CTSL (0.42) | FOLH1NPY1RNPY2RNPY4RIL1RN | |
| SCHEMBL7540855 | 0.82 | CTSL (0.40) | FOLH1NPY1RNPY2RNPY4RACE | |
| SCHEMBL7544736 | 0.82 | NPY4R (0.42) | FOLH1NPY1RNPY2RNPY4RIL1RN | |
| SCHEMBL7546168 | 0.82 | ITGB1 (0.54) | FOLH1ACEMMECPA1ACE2 | |
| SCHEMBL7540570 | 0.82 | ITGB1 (0.54) | FOLH1ACEMMECPA1ACE2 | |
| SCHEMBL7538222 | 0.82 | CTSL (0.39) | FOLH1NPY1RNPY2RNPY4RACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |