Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301281 | 1.00 | ALDH1A1 (0.59) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL5469857 | 0.90 | CYP2A6 (0.50) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL3074403 | 0.90 | CYP2A6 (0.50) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL9640411 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL9640413 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL2316309 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP2A6MAPTMEN1KMT2A | |
| SCHEMBL15355549 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL13451257 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL15132514 | 0.79 | ALDH5A1 (0.73) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28987870 | 0.79 | PTGS1 (0.44) | ALDH1A1CYP2A6MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106434871-B | Methods and compositions for detecting target nucleic acids | 德克斯特里蒂诊断公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-103827317-B | Methods and compositions for detecting target nucleic acids | 德克斯特里蒂诊断公司 | 2016-09-07 | — | — | CN | disclosed |
| US-20140121226-A1 | SUBSTITUTED XANTHINE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2014-05-01 | — | — | US | disclosed |
| EP-2314713-A1 | OLIGONUCLEOTIDE PROBE, AND USE THEREOF | National University Corporation Nagoya University (JP) | 2011-04-27 | — | — | EP | disclosed |
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
| US-4285852-A | Anisotropic wholly aromatic polyester derived from 4-hydroxy-4'-carboxy azobenzene and process for preparation | CELANESE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-3987037-A | RADIATION-SENSITIVE FREE RADICAL GENERATORS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3954475-A | Photosensitive elements containing chromophore-substituted vinyl-halomethyl-s-triazines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | ALDH1A1 1488/4885CYP2A6 1575/4885MAPT 3240/4885 |
| US-20140121226-A1 | SUBSTITUTED XANTHINE DERIVATIVES | XDH, CXCR4, CXCR3 | ALDH1A1 927/4885CYP2A6 507/4885MAPT 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.