Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30841853 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL339966 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL28129115 | 0.77 | TK1 (0.43) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL3477 | 0.77 | TK1 (0.43) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL28765909 | 0.77 | LMNA (0.42) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL2294 | 0.77 | TK1 (0.43) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL29943756 | 0.77 | TK1 (0.43) | LMNAALDH1A1ALBBLMPOLB | |
| Hydrochloric Acid SCHEMBL28100272 | 0.76 | TK1 (0.42) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL2012504 | 0.74 | ALDH1A1 (0.43) | LMNAALDH1A1ALBBLMPOLB | |
| SCHEMBL6830454 | 0.74 | TK1 (0.43) | LMNAALDH1A1ALBBLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126085-A1 | CELL DIFFERENTIATION BASED UPON PARTICLE UPTAKE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1984-11-28 | — | — | EP | claimed |
| WO-1984000815-A1 | CELL DIFFERENTIATION BASED UPON PARTICLE UPTAKE | MASSACHUSETTS INST TECHNOLOGY (US) | 1984-03-01 | — | — | WO | claimed |
| EP-0149040-B2 | Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same | NOVAGENE INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-5935829-A | DETERMINING MUTAGENICITY OF COMPOUNDS BY EXPOSING HUMAN LYMPHOBLASTOID CELL LINE TO CHEMICAL REQUIRING ACTIVATION BY OXIDATIVE ENZYMES, CULTURING CELLS, DETECTING NUMBER OF MUTANT CELLS, COMPARING FREQUENCY OF MUTATION TO CONTROLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-08-10 | — | — | US | disclosed |
| US-5429948-A | Human cell line stably expressing 5cDNAS encoding procarcinogen-activating enzymes and related mutagenicity assays | GENTEST CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0149040-B1 | MODIFIED LIVE PSEUDORABIES VIRUSES, VACCINES FOR PSEUDORABIES DISEASE CONTAINING SAME, METHODS FOR PRODUCTION OF SAME AND METHODS FOR USE OF SAME | NOVAGENE, INC. (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0113769-B1 | MUTATION ASSAYS INVOLVING BLOOD CELLS THAT METABOLIZE TOXIC SUBSTANCES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4609548-A | NON-PRODUCERS OF THYMIDINE KINASE; VETERINARY MEDICINE | NOVAGENE, LTD. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4532204-A | Exposing culture of AHH-1 cells to substance, comparing frequency of mutation to that of unexposed cells to determine mutagenicity | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1985-07-30 | — | — | US | disclosed |
| EP-0149040-A2 | Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same | NOVAGENE, INC. (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4514497-A | DO NOT PRODUCE THYMIDINE KINASE- TEMPERATURE RESISTANCE | NOVAGENE, LTD. (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0113769-A1 | MUTATION ASSAYS INVOLVING BLOOD CELLS THAT METABOLIZE TOXIC SUBSTANCES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1984-07-25 | — | — | EP | disclosed |
| WO-1984000379-A1 | MUTATION ASSAYS INVOLVING BLOOD CELLS THAT METABOLIZE TOXIC SUBSTANCES | MASSACHUSETTS INST TECHNOLOGY (US) | 1984-02-02 | — | — | WO | disclosed |