SCHEMBL7544283

SCHEMBL7544283

CCCC(CC(C)C)=C(C#N)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7547018 0.90 CES1 (0.34) ALDH1A1TDP1
SCHEMBL7542236 0.88 AKR1B1 (0.38) ALDH1A1TDP1
SCHEMBL7543407 0.87 GPR84 (0.40) ALDH1A1TDP1
SCHEMBL7544413 0.87 GPR84 (0.40) ALDH1A1TDP1
SCHEMBL7548122 0.85 GRIK1 (0.35) ALDH1A1TDP1
SCHEMBL8600596 0.85 HDAC3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL19357539 0.81 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL3923583 0.81 FFAR3 (0.37) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL7552128 0.78 CES1 (0.39) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL7546476 0.73 CES1 (0.41) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US disclosed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF FFAR3 1623/4885HDAC3 3316/4885HDAC1 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.