SCHEMBL754556

SCHEMBL754556

CC1=CC(=O)C(N)=CC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.46
PLK1 P53350 1/20 0.46
PLK2 Q9NYY3 1/20 0.46
STAT3 P40763 1/20 0.43
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34
MEN1 O00255 3/20 0.34
USP2 O75604 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
MAPK1 P28482 2/20 0.34
BLM P54132 2/20 0.34
LMNA P02545 2/20 0.34
PLIN1 O60240 1/20 0.34
NR1I2 O75469 1/20 0.34
GSR P00390 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
ADORA3 P0DMS8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xyloquinone SCHEMBL49964 0.82 PLK1 (0.60) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL4964070 0.82 NSD2 (0.43) ALDH1A1MAPTMEN1USP2KMT2A
Bromide SCHEMBL11511582 0.78 NSD2 (0.42) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL11237515 0.77 SLC2A1 (0.41) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL14507718 0.71 PLK1 (0.50) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL21819582 0.68 NSD2 (0.43) ALDH1A1MAPTMEN1USP2KMT2A
SCHEMBL3624714 0.68 ALDH1A1 (0.50) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL7946964 0.67 PLK1 (0.46) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL2931396 0.67 EEF2K (0.46) EEF2KPLK1PLK2STAT3ALDH1A1
SCHEMBL11704367 0.67 PLK1 (0.46) EEF2KPLK1PLK2STAT3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 EP claimed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 US claimed
WO-2006094217-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-09-08 WO claimed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 US claimed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 US claimed
EP-4419580-B1 METHOD FOR PROMOTING HYDROSILYLATION REACTION TO PREPARE ESTER-FUNCTIONAL SILOXANE OLIGOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-27 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
EP-4172165-B1 PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS DOW SILICONES CORP (US) 2025-07-23 EP disclosed
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS DOW SILICONES CORP (US) 2025-05-01 US disclosed
US-20250136625-A1 PROCESS FOR THE PREPARATION OF ORGANIC SILICON COMPOUNDS BASF SE (DE) 2025-05-01 US disclosed
WO-2003104302-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED TRIMETHYLOLPROPANE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104299-A1 METHOD FOR THE PRODUCTION OF ESTERS OF POLYALCOHOLS BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003104301-A1 (METH)ACRYLIC ESTERS OF POLYALKOXYLATED GLYCERINE BASF AKTIENGESELLSCHAFT (DE) 2003-12-18 WO disclosed
WO-2003099757-A1 STABILISATION OF ETHYLENICALLY UNSATURATED COMPOUNDS COMPRISING HYDROXYLAMINE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-12-04 WO disclosed
WO-2003057657-A1 METHOD FOR PRODUCING ACRYLIC ACID BASF AKTIENGESELLSCHAFT (DE) 2003-07-17 WO disclosed
WO-2003042199-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2003-05-22 WO disclosed
WO-2003035596-A2 INHIBITOR MIXTURE FOR (METH)ACRYLIC ACID AND (METH)ACRYLIC ACID ESTER BASF AKTIENGESELLSCHAFT (DE) 2003-05-01 WO disclosed
US-20030060654-A1 Preparation of polymerizable compounds BASF AKIENGESELLSCHAFT (DE) 2003-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 EEF2K 1733/4885PLK1 4470/4885PLK2 3458/4885
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives KRT18, NDUFA1, NDUFA2 EEF2K 4034/4885PLK1 1188/4885PLK2 1258/4885
US-20250136763-A1 SILICONE - VINYLESTER FUNCTIONAL COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN PERSONAL CARE COMPOSITIONS VCL, FANCF, MMS19 EEF2K 3158/4885PLK1 4416/4885PLK2 618/4885
US-20070000073-A1 Agent and method for colouring keratin fibres KRT18, CDC73, OAT EEF2K 3511/4885PLK1 1027/4885PLK2 1286/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 EEF2K 4411/4885PLK1 3219/4885PLK2 2789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.