Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556390 | 0.88 | NAPRT (0.37) | NAMPTKDRMEN1KMT2ARAB9A | |
| SCHEMBL7549098 | 0.83 | RAB9A (0.41) | NAMPTKDRRAB9AMAPTNPC1 | |
| SCHEMBL7600813 | 0.80 | — | — | |
| SCHEMBL7548471 | 0.78 | MAPK13 (0.41) | ALDH1A1NAPRTNOS3NOS2 | |
| SCHEMBL7553256 | 0.77 | RAB9A (0.40) | NAMPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL9060466 | 0.76 | NOS3 (0.40) | KDRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL7549213 | 0.75 | L3MBTL1 (0.41) | KDRRAB9AALDH1A1MAPTLMNA | |
| SCHEMBL7546196 | 0.74 | KDM4E (0.38) | RAB9ANPC1NOS3NOS2LIMK1 | |
| SCHEMBL7553486 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNANAPRTNOS3 | |
| SCHEMBL7550244 | 0.74 | MAPK14 (0.35) | KDRKMT2ARAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |