Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS2 | P35228 | 3/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799100 | 0.89 | KDM4E (0.44) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL7600813 | 0.83 | — | — | |
| SCHEMBL7549098 | 0.79 | RAB9A (0.41) | GSK3BNPC1PPARGRAB9ANCOR2 | |
| SCHEMBL7546276 | 0.78 | MEN1 (0.45) | KDM4ENPC1NOS3NOS2 | |
| SCHEMBL7546252 | 0.77 | TDP1 (0.32) | PPARGNOS3NOS2TP53 | |
| SCHEMBL7545898 | 0.74 | NAMPT (0.36) | NPC1RAB9ANOS3NOS2LIMK1 | |
| SCHEMBL7548395 | 0.74 | ALOX5 (0.38) | ALOX5NPC1RAB9A | |
| SCHEMBL9059987 | 0.74 | SGMS2 (0.35) | KDM4EKDM4CTP53 | |
| SCHEMBL9059311 | 0.72 | NAPRT (0.34) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL8799386 | 0.71 | SHBG (0.44) | KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |