SCHEMBL7546534

SCHEMBL7546534

Cc1ccc(Oc2ccccc2O)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
TRPA1 O75762 1/20 0.46
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
AR P10275 1/20 0.42
GAA P10253 2/20 0.41
LMNA P02545 2/20 0.41
JAK2 O60674 1/20 0.41
MAPT P10636 1/20 0.41
TTR P02766 1/20 0.41
SLC6A4 P31645 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10292484 0.89 TRPA1 (0.56) CA1CA2TP53TRPA1AR
SCHEMBL5607173 0.85 ALDH1A1 (0.56) TRPA1IDO1TDO2GAAMAPT
SCHEMBL5168243 0.83 LMNA (0.49) CA1CA2TP53TSHRTRPA1
SCHEMBL6186016 0.83 ALDH1A1 (0.48) CA1CA2TP53TSHRIDO1
SCHEMBL29355313 0.82 TTR (0.61) TRPA1ARGAATTR
SCHEMBL7006874 0.82 TTR (0.61) TRPA1ARGAATTR
SCHEMBL16325968 0.82 TP53 (0.52) TP53TRPA1ARGAALMNA
SCHEMBL5607286 0.81 IDO1 (0.40) TRPA1IDO1TDO2ARSLC6A4
SCHEMBL5143178 0.81 AR (0.54) IDO1ARGAAMAPT
SCHEMBL18197 0.80 CA2 (0.62) CA1CA2TP53TSHRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO claimed
WO-2002050008-A2 NON-HALOGENATED PHENOXY AND/OR BENZYLOXY PHENOLS AND ANTIMICROBIAL COMPOSITIONS CONTAINING THEM WARNER-LAMBERT COMPANY LLC (US) 2002-06-27 WO disclosed