SCHEMBL7546576

SCHEMBL7546576

CCc1ccc(S(=O)(=O)O)c(CC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
ALDH1A1 P00352 4/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA2 P00918 1/20 0.39
HPGD P15428 2/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
BACE1 P56817 1/20 0.38
MEN1 O00255 2/20 0.38
USP2 O75604 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28071605 0.98 TRPA1 (0.41) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL2057730 0.86 EDNRB (0.37) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL2622530 0.84 ALDH1A1 (0.47) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL2057922 0.84 EDNRB (0.36) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL20867903 0.83 ALDH1A1 (0.41) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL1607447 0.82 ESR2 (0.41) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL9185361 0.82 TRPA1 (0.55) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL2057871 0.81 EDNRB (0.37) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL8452866 0.81 CA2 (0.41) TRPA1ALDH1A1LMNAMAPTNPC1
SCHEMBL11710560 0.80 KAT8 (0.46) ALDH1A1LMNACA2HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020038049-A1 SULPHONATION PROCESS AND NOVEL SULPHONATED COMPOUNDS MANRO PERFOMANCE CHEMICALS LIMITED (GB) 2002-03-28 US claimed
EP-0998453-A1 SULPHONATION PROCESS AND NOVEL SULPHONATED COMPOUNDS Manro Performance Chemicals Limited (GB) 2000-05-10 EP claimed
WO-1999061415-A1 SULPHONATION PROCESS AND NOVEL SULPHONATED COMPOUNDS MANRO PERFORMANCE CHEMICALS LIMITED (GB) 1999-12-02 WO claimed
CN-110964006-A Organic electroluminescent device and amine compound for organic electroluminescent device 三星显示有限公司 2020-04-07 CN disclosed
CN-102558141-A Method for refining 2,4-diethyl thioxathone LANZHOU PETROCHEMICAL COLLEGE OF VOCATIONAL TECHNOLOGY 2012-07-11 CN disclosed
US-20020038049-A1 SULPHONATION PROCESS AND NOVEL SULPHONATED COMPOUNDS MANRO PERFOMANCE CHEMICALS LIMITED (GB) 2002-03-28 US disclosed
EP-0159755-A2 Isomerization of tertiary olefins SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020038049-A1 SULPHONATION PROCESS AND NOVEL SULPHONATED COMPOUNDS TST, STS, SULT2A1 TRPA1 43/4885ALDH1A1 2453/4885LMNA 4851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.