Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546276 | 0.88 | MEN1 (0.45) | MAPTMEN1KMT2ASHBGCTBP2 | |
| SCHEMBL8805065 | 0.84 | SHBG (0.44) | MEN1KMT2ASHBGCTBP2NAPRT | |
| SCHEMBL7551790 | 0.83 | SGMS2 (0.36) | MAPTSHBGNAPRTHTTNR3C2 | |
| SCHEMBL7546700 | 0.81 | ALOX5 (0.39) | MEN1KMT2ANAPRTKDM4E | |
| SCHEMBL9059311 | 0.80 | NAPRT (0.34) | KMT2ANAPRTKDM4EKDM4CKDM5B | |
| SCHEMBL7546681 | 0.78 | TDP1 (0.37) | KMT2ANAPRTKDM4ENOS3NOS2 | |
| SCHEMBL7553608 | 0.78 | NAPRT (0.46) | KMT2ANAPRTALDH1A1HPGDKDM5A | |
| SCHEMBL8799100 | 0.77 | KDM4E (0.44) | KMT2ANAPRTKDM4EKDM4CKDM5B | |
| SCHEMBL8798744 | 0.76 | NAPRT (0.44) | KMT2ANAPRTKDM4EALDH1A1HPGD | |
| SCHEMBL7547531 | 0.76 | NAPRT (0.44) | KMT2ANAPRTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |