SCHEMBL286906

SCHEMBL286906

O=C(Cl)Cc1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.56
PKM P14618 1/20 0.55
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KCNJ5 P48544 2/20 0.49
KCNJ3 P48549 2/20 0.49
PNMT P11086 1/20 0.48
IDO1 P14902 1/20 0.48
KMT2A Q03164 2/20 0.47
SHBG P04278 1/20 0.47
APAF1 O14727 1/20 0.47
TDP2 O95551 1/20 0.47
NSD2 O96028 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KDM4C Q9H3R0 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
UBA2 Q9UBT2 1/20 0.47
ERCC1 P07992 1/20 0.46
ERCC4 Q92889 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29810302 1.00 CTBP2 (0.56) CTBP2PKMNPC1RAB9AKCNJ5
SCHEMBL11776630 0.92 CXCL8 (0.57) CTBP2PKMNPC1RAB9ACXCL8
SCHEMBL6767819 0.85 AKR1B1 (0.46) CTBP2PKMNPC1RAB9AALDH1A1
SCHEMBL3086828 0.84 PNMT (0.56) CTBP2NPC1RAB9APNMTIDO1
SCHEMBL1091961 0.84 PKM (0.64) CTBP2PKMNPC1RAB9AKCNJ5
SCHEMBL6194349 0.84 CTBP2 (0.58) CTBP2PKMNPC1RAB9AKCNJ5
SCHEMBL31365969 0.84 CTBP2 (0.58) CTBP2PKMNPC1RAB9AKCNJ5
Hydrochloric Acid SCHEMBL7827446 0.83 PKM (0.62) CTBP2PKMNPC1RAB9AKCNJ5
SCHEMBL29933245 0.82 CXCL8 (0.65) CTBP2PKMNPC1RAB9ACXCL8
SCHEMBL6960850 0.82 CTBP2 (0.56) CTBP2PKMNPC1RAB9AKCNJ5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN claimed
CN-117986231-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-116199617-A Oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-116199616-A Modified oxime ester compound, preparation method thereof and photo-curing composition 常州强力电子新材料股份有限公司 2023-06-02 CN claimed
CN-115399179-A Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry 中国科学院化学研究所 2022-11-29 CN claimed
CN-112851547-A Fluorenoxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2021-05-28 CN claimed
CN-108863774-A A kind of 2,4 dichloro benzene chloroacetic chloride synthetic method 石家庄市绿丰化工有限公司 2018-11-23 CN claimed
CN-103420823-B The synthetic method of ��-chloro-4 fluorophenyl benzyl ketones 南京欧信医药技术有限公司 2016-06-08 CN claimed
CN-103936552-B A kind of epoxiconazole intermediate (Z)-2-(4-fluorophenyl)-1-(2-chloro-phenyl-) preparation method of-3-propylene halide SINOCHEM CORPORATION (CN) 2015-11-18 CN claimed
CN-103254027-B One prepares the method for 1,2-diphenyl propylene compound SINOCHEM CORPORATION (CN) 2015-09-23 CN claimed
CN-103936552-A Preparation method of epoxiconazole intermediate (Z)-2-(4-fluorophenyl)-1-(2-chlorphenyl)-3-halogen propylene SINOCHEM CORP 2014-07-23 CN claimed
EP-1323714-B1 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals PRESIDENT OF GIFU UNIVERSITY (JP) 2006-09-20 EP claimed
US-20030158239-A1 Novel 1,3-selenazolin derivatives and process for preparing the same GIFU UNIVERSITY (JP) 2003-08-21 US claimed
EP-1323714-A1 1,3-selenazole derivatives and their use as anticancer drugs or as agrochemicals President of Gifu University (JP) 2003-07-02 EP claimed
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECH LIMITED (GB) 2026-05-21 US disclosed
US-12605353-B2 PDIA4 inhibitors and use thereof for inhibiting β-cell pathogenesis and treating diabetes ACADEMIA SINICA (TW) 2026-04-21 US disclosed
US-4013652-A SEDATIVES ENDO LABORATORIES, INC. (US) 1977-03-22 US disclosed
US-3992396-A TRANQUILIZERS, HYPNOTICS SANDOZ, INC. (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER EGFR, KRAS, O60361 CTBP2 3460/4885PKM 4823/4885NPC1 386/4885
US-12605353-B2 PDIA4 inhibitors and use thereof for inhibiting β-cell pathogenesis and treating diabetes PDIA4, PDIA5, PDIA6 CTBP2 3586/4885PKM 1342/4885NPC1 1919/4885
US-20030158239-A1 Novel 1,3-selenazolin derivatives and process for preparing the same SELENOI, SCLY, SULT1A1 CTBP2 2940/4885PKM 3988/4885NPC1 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.