Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805065 | 0.90 | SHBG (0.44) | SHBGPKMCASP3SENP8SENP7 | |
| SCHEMBL7546276 | 0.86 | MEN1 (0.45) | SHBGKMT2AALDH1A1KDM4ECTBP2 | |
| SCHEMBL7548003 | 0.82 | SHBG (0.44) | SHBGPKMCASP3SENP8SENP7 | |
| SCHEMBL8800986 | 0.78 | RECQL (0.48) | PKMKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7548395 | 0.77 | ALOX5 (0.38) | PKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7549390 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1CYP3A4 | |
| SCHEMBL7600813 | 0.76 | — | — | |
| SCHEMBL9059987 | 0.74 | SGMS2 (0.35) | SHBGKMT2AKDM4EMAPK1MEN1 | |
| SCHEMBL7547894 | 0.74 | MAPT (0.46) | SHBGKMT2AALDH1A1KDM4ECTBP2 | |
| SCHEMBL7546252 | 0.72 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |