Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7554322 | 0.90 | MMP1 (0.46) | L3MBTL1MMP1MMP3S1PR5KCNH2 | |
| Hydroxyamine SCHEMBL7551188 | 0.88 | MMP13 (0.48) | MMP1TSHRALDH1A1SMN1; SMN2MMP9 | |
| SCHEMBL7510558 | 0.88 | MMP1 (0.47) | L3MBTL1MMP1MMP3S1PR5KCNH2 | |
| SCHEMBL7511232 | 0.87 | S1PR5 (0.48) | L3MBTL1MMP1S1PR5HTR2AALDH1A1 | |
| SCHEMBL7510431 | 0.87 | KCNH2 (0.51) | L3MBTL1MMP1MMP3KCNH2TSHR | |
| SCHEMBL7510655 | 0.86 | L3MBTL1 (0.49) | L3MBTL1MMP1MMP3S1PR5KCNH2 | |
| SCHEMBL7512305 | 0.85 | S1PR5 (0.47) | L3MBTL1MMP1S1PR5ALDH1A1RAB9A | |
| SCHEMBL7643949 | 0.84 | NPSR1 (0.47) | L3MBTL1MMP1MMP3S1PR5MAPK1 | |
| Hydroxyamine SCHEMBL7661687 | 0.84 | MMP1 (0.51) | MMP1S1PR5KCNH2TSHRS1PR1 | |
| Hydroxyamine SCHEMBL7556400 | 0.84 | MMP1 (0.50) | L3MBTL1MMP1S1PR5ALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006922-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | L3MBTL1 3486/4885MMP1 7/4885MMP3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.