SCHEMBL7548155

SCHEMBL7548155

Fc1cc(C(Cl)Cl)c(Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM1A O60341 2/20 0.32
KDM1B Q8NB78 1/20 0.32
MAPT P10636 1/20 0.32
GPR84 Q9NQS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12309968 0.78 GABRA1 (0.38) ALDH1A1TDP1KDM1AKDM1BMAPT
SCHEMBL9623249 0.78 LMNA (0.33) ALDH1A1
SCHEMBL171637 0.75 HTR2A (0.33) ALDH1A1TDP1
SCHEMBL14800299 0.75 PDE2A (0.47) ALDH1A1TDP1
SCHEMBL18599419 0.75 LMNA (0.50) ALDH1A1TDP1KDM1AKDM1B
SCHEMBL7534006 0.74 ALDH1A1 (0.46) ALDH1A1TDP1KDM1AKDM1BMAPT
SCHEMBL7940907 0.72 AHR (0.44) ALDH1A1TDP1KDM1AKDM1BMAPT
SCHEMBL17227607 0.72 TSHR (0.35) ALDH1A1TDP1
SCHEMBL23351729 0.71 KDM1A (0.48) ALDH1A1TDP1KDM1AKDM1BMAPT
SCHEMBL27926241 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439620-A CHEMICAL INTERMEDIATE BAYER AKTIENGESELLSCHAFT (DE) 1984-03-27 US claimed
EP-0872476-B1 Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds BAYER AG (DE) 2002-07-03 EP disclosed
EP-0872476-A2 Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds BAYER AG (DE) 1998-10-21 EP disclosed
US-5824817-A Herbicidal compositions based on 2,6-dichloro-3-fluoro-benzonitrile, and new intermediates BAYER AKTIENGESELLSCHAFT (DE) 1998-10-20 US disclosed
EP-0713862-B1 Herbicidal substance based on 2,6-dichloro-3-fluoro- benzonitrile. BAYER AG (DE) 1998-09-16 EP disclosed
US-5723613-A Process for the free-radical chlorination or bromination of methyl aromatic compounds BAYER AKTIENGESELLSCHAFT (DE) 1998-03-03 US disclosed
EP-0653412-B1 Process for preparing 4,5-difluorobenzaldehydes BAYER AG (DE) 1998-01-21 EP disclosed
EP-0537540-B1 Process for the radical chlorination or bromination of methyl substituted aromatics BAYER AG (DE) 1996-10-23 EP disclosed
EP-0713862-A2 Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds BAYER AG (DE) 1996-05-29 EP disclosed
US-5489715-A Process for preparing 4,5-difluorobenzaldehydes BAYER AKTIENGESELLSCHAFT (DE) 1996-02-06 US disclosed
EP-0653412-A1 Process for preparing 4,5-difluorobenzaldehydes BAYER AG (DE) 1995-05-17 EP disclosed
EP-0537540-A1 Process for the radical chlorination or bromination of methyl substituted aromatics BAYER AG (DE) 1993-04-21 EP disclosed
US-4439620-A CHEMICAL INTERMEDIATE BAYER AKTIENGESELLSCHAFT (DE) 1984-03-27 US disclosed