SCHEMBL8064655

SCHEMBL8064655

CSCn1ccc(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
CRBN Q96SW2 3/20 0.48
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
DUT P33316 8/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
ENPP1 P22413 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4347791 0.84 ALDH1A1 (0.50) PKMCRBNALDH1A1LMNADUT
SCHEMBL7752441 0.81 PKM (0.38) PKMCRBNALDH1A1LMNADUT
SCHEMBL14086528 0.81 CRBN (0.50) PKMCRBNALDH1A1LMNADUT
SCHEMBL1923335 0.78 PKM (0.61) PKMCRBNALDH1A1LMNADUT
SCHEMBL338055 0.78 ALDH1A1 (0.56) PKMCRBNALDH1A1LMNADUT
SCHEMBL10924758 0.77 PKM (0.55) PKMCRBNALDH1A1LMNADUT
SCHEMBL4348697 0.77 L3MBTL1 (0.59) PKMCRBNALDH1A1LMNADUT
SCHEMBL11983580 0.76 ALDH1A1 (0.58) PKMCRBNALDH1A1LMNADUT
SCHEMBL6102943 0.75 CRBN (0.56) PKMCRBNALDH1A1LMNADUT
SCHEMBL4286089 0.74 PKM (0.57) PKMCRBNDUTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7501429-B2 Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-03-10 US disclosed
US-7501429-B2 Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-03-10 US disclosed
EP-0823068-B1 COLOR-PROVIDING COMPOUNDS POLAROID CORP (US) 2000-08-09 EP disclosed
EP-0861456-B1 IMAGE-RECORDING MATERIALS POLAROID CORP (US) 2000-06-21 EP disclosed
EP-0823069-B1 IMAGE-RECORDING ELEMENT POLAROID CORP (US) 1999-06-02 EP disclosed
US-5811530-A MONOAZO CYAN DYE CHROMOPHOR HAVING A BENZOISOTHIAZOLE MOIETY, DIFFUSION CONTROL GROUP; FOR PEEL-APART PHOTOGRAPHIC FILMS POLAROID CORPORATION (US) 1998-09-22 US disclosed
EP-0861456-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1998-09-02 EP disclosed
WO-1998012602-A1 IMAGE-RECORDING MATERIALS POLAROID CORPORATION (US) 1998-03-26 WO disclosed
EP-0823069-A1 IMAGE-RECORDING ELEMENT POLAROID CORPORATION (US) 1998-02-11 EP disclosed
EP-0823068-A1 COLOR-PROVIDING COMPOUNDS POLAROID CORPORATION (US) 1998-02-11 EP disclosed
US-5717079-A CONTAINING AT LEAST TWO 1,3-SULFUR-NITROGEN MOIETIES AND A COMPLETE DYE OR DYE INTERMEDIATE POLAROID CORPORATION (US) 1998-02-10 US disclosed
US-5716754-A INCLUDING IMAGE DYE-PROVIDING COMPOUND COMPRISING NAPHTHOL AZO CYAN DYE HAVING 3-AMINOBENZISOTHIAZOLE MOIETY POLAROID CORPORATION (US) 1998-02-10 US disclosed
US-5667933-A PHOTOSENSITIVE IMAGES RECORDING ELEMENTS FOR THERMAL IMAGES POLAROID CORPORATION (US) 1997-09-16 US disclosed
WO-1997031295-A1 COLOR-PROVIDING COMPOUNDS POLAROID CORPORATION (US) 1997-08-28 WO disclosed
WO-1997031296-A1 IMAGE-RECORDING ELEMENT POLAROID CORPORATION (US) 1997-08-28 WO disclosed
US-5658705-A HEAT DEVELOPABLE POLAROID CORPORATION (US) 1997-08-19 US disclosed