Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782067 | 0.88 | BACE1 (0.38) | LTA4HMGLLGPR142FAAH | |
| SCHEMBL757503 | 0.83 | PIK3CD (0.36) | GPR142FAAH | |
| SCHEMBL760502 | 0.83 | FFAR1 (0.38) | GPR142FAAH | |
| SCHEMBL759900 | 0.82 | FAAH (0.44) | GPR142FAAH | |
| SCHEMBL756393 | 0.79 | GPR142 (0.38) | MGLLGPR142FAAH | |
| SCHEMBL755478 | 0.79 | LMNA (0.46) | GPR142 | |
| SCHEMBL757739 | 0.78 | KEAP1 (0.43) | LTA4HMGLLFAAH | |
| SCHEMBL759673 | 0.75 | MAPT (0.43) | FAAH | |
| SCHEMBL782015 | 0.72 | GPR119 (0.38) | — | |
| SCHEMBL758615 | 0.72 | TDP1 (0.45) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431360-B1 | Derivatives of dihydrobenzoxathiazepine, method of preparing same and pharmaceutical compositions containing them as well as their uses as modulators of AMPA receptors | SERVIER LAB (FR) | 2013-04-17 | — | — | EP | disclosed |
| EP-2431360-A1 | Derivatives of dihydrobenzoxathiazepine, method of preparing same and pharmaceutical compositions containing them as well as their uses as modulators of AMPA receptors | Les Laboratoires Servier (FR) | 2012-03-21 | — | — | EP | disclosed |