SCHEMBL755213

SCHEMBL755213

CCCCC(CC)CC(=C(OC)C(=O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 2/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 3/20 0.46
MAPK1 P28482 3/20 0.46
KDM4E B2RXH2 1/20 0.42
HDAC3 O15379 4/20 0.41
HDAC1 Q13547 4/20 0.41
HDAC2 Q92769 4/20 0.41
HDAC8 Q9BY41 4/20 0.41
HDAC6 Q9UBN7 4/20 0.41
HDAC4 P56524 3/20 0.41
HDAC7 Q8WUI4 3/20 0.41
HDAC10 Q969S8 3/20 0.41
HDAC11 Q96DB2 3/20 0.41
HDAC9 Q9UKV0 3/20 0.41
HDAC5 Q9UQL6 3/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605462 1.00 ALDH1A1 (0.46) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL29715037 0.88 ALDH1A1 (0.45) ALDH1A1CYP3A4CA2LMNAMAPK1
4-Methoxycinnamic Acid SCHEMBL1914841 0.85 TDP1 (0.54) ALDH1A1CYP3A4LMNAKMT2AMEN1
SCHEMBL5164920 0.84 HDAC3 (0.43) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL7088150 0.80 HDAC3 (0.40) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL530371 0.80 TDP1 (0.58) CYP3A4LMNAKMT2AMEN1SMN1; SMN2
SCHEMBL30146881 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4CA2LMNAMAPK1
SCHEMBL5178120 0.79 PTGS2 (0.57) ALDH1A1PTGS2
SCHEMBL8576549 0.78 ALDH1A1 (0.62) ALDH1A1CYP3A4CA2LMNAMAPK1
Zinc Ion SCHEMBL29663961 0.78 HDAC3 (0.38) ALDH1A1CYP3A4CA2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768228-B1 COMPOSITION USEFUL FOR SLOWING DOWN DEGRADATION CAUSED BY LIGHT, HEAT AND/OR OXIDATION OF A COSMETICALLY ACTIVE COMPOUND SENSIENT COSMETIC TECH (FR) 2024-08-14 EP claimed
EP-2775997-B1 COSMETIC AND DERMATOLOGICAL PHOTOPROTECTIVE PREPARATION WITH IMPROVED WATER RESISTANCE BEIERSDORF AG (DE) 2019-08-07 EP claimed
EP-2442788-B1 METHODS FOR IMPROVING THE APPEARANCE OF HYPERPIGMENTED SPOT(S) USING AN EXTRACT OF LAMINARIA SACCHARINA PROCTER & GAMBLE (US) 2016-08-31 EP claimed
EP-2985018-A1 ANTI-DISCOLORATION COMPOSITION Sensient Cosmetic Technologies (FR) 2016-02-17 EP claimed
EP-1755543-B1 ANTI-COLOUR FADING COMPOSITION SENSIENT COSMETIC TECHNOLOGIES (FR) 2015-10-28 EP claimed
WO-2015028424-A1 EMULSIFIER-FREE, SKIN-CONDITIONING COSMETIC OR DERMATOLOGICAL PREPARATION WITH LIGHT-PROTECTION FILTERS BEIERSDORF AG (DE) 2015-03-05 WO claimed
US-8496916-B2 Sunscreen composition with polyhydroxy quaternary ammonium salts CONOPCO, INC. (US) 2013-07-30 US claimed
WO-2013076149-A2 SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS UNILEVER PLC (GB) 2013-05-30 WO claimed
US-20130129644-A1 SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS CONOPCO, INC., D/B/A UNILEVER (US) 2013-05-23 US claimed
CN-101170990-B Skin lightening composition comprising a conjugated linoleic acid and niacinamide UNILEVER NV 2012-11-07 CN claimed
EP-1278510-B1 DETERGENT BAR COMPOSITION WITH SKIN LIGHTENING AGENTS AND ORGANIC SUNSCREEN UNILEVER PLC (GB) 2005-03-16 EP claimed
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US claimed
EP-0910335-B1 INSECT REPELLENT SUNSCREEN JOHNSON & SON INC S C (US) 2002-10-16 EP claimed
EP-1011629-A1 CLEANSING AND CONDITIONING PRODUCTS FOR SKIN OR HAIR WITH IMPROVED DEPOSITION OF CONDITIONING INGREDIENTS THE PROCTER & GAMBLE COMPANY (US) 2000-06-28 EP claimed
EP-0934056-A1 CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1999-08-11 EP claimed
WO-1999012519-A1 CLEANSING AND CONDITIONING PRODUCTS FOR SKIN OR HAIR WITH IMPROVED DEPOSITION OF CONDITIONING INGREDIENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-18 WO claimed
EP-0841898-A1 TOPICAL COMPOSITIONS HAVING IMPROVED SKIN FEEL THE PROCTER & GAMBLE COMPANY (US) 1998-05-20 EP claimed
WO-1998018441-A1 CLEANSING PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1998-05-07 WO claimed
WO-1997003647-A1 TOPICAL COMPOSITIONS HAVING IMPROVED SKIN FEEL THE PROCTER & GAMBLE COMPANY (US) 1997-02-06 WO claimed
EP-0396422-B1 Skin composition UNILEVER PLC (GB) 1994-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130129644-A1 SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS MMS19, RAD23B, DDAH1 ALDH1A1 1939/4885CYP3A4 3013/4885CA2 2388/4885
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, ALAD, HMBS ALDH1A1 107/4885CYP3A4 290/4885CA2 2971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.