Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552512 | 1.00 | TDP1 (0.41) | TDP1HPGDPARP1ALDH1A1MAPT | |
| SCHEMBL9562364 | 0.84 | CES2 (0.41) | HPGDALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9562359 | 0.84 | CES2 (0.41) | HPGDALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11872290 | 0.73 | HPGD (0.66) | TDP1HPGDPARP1ALDH1A1MAPT | |
| SCHEMBL2060236 | 0.71 | PARP1 (0.61) | TDP1HPGDPARP1ALDH1A1MAPT | |
| SCHEMBL29922789 | 0.71 | PARP1 (0.61) | TDP1HPGDPARP1ALDH1A1MAPT | |
| SCHEMBL10784885 | 0.71 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL12879204 | 0.70 | HPGD (0.74) | TDP1HPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3753879 | 0.69 | PARP1 (0.68) | TDP1HPGDPARP1SMN1; SMN2HDAC8 | |
| SCHEMBL7668976 | 0.68 | PARP1 (0.45) | TDP1HPGDPARP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2002-12-19 | — | — | US | disclosed |
| EP-1167344-A1 | PROCESS FOR PRODUCING 5-AMINO-8- ALKYLQUINOLO NECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES IN THE PRODUCTION THEREOF | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193591-A1 | Process for producing 5-amino-8-alkylquinolonecarboxylic acid derivative and intermediates in the production thereof | SQOR, XDH, SPOUT1 | TDP1 4216/4885HPGD 404/4885PARP1 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.