SCHEMBL755371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL765804	0.85	ALDH1A1 (0.38)	POLBALDH1A1CYP1A2CYP2D6CYP2C9
	SCHEMBL765090	0.80	ALDH1A1 (0.40)	L3MBTL1POLBALDH1A1CYP1A2CYP2D6
	SCHEMBL755003	0.77	SMN1; SMN2 (0.38)	SMN1; SMN2MAPTL3MBTL1POLBTDP1
	SCHEMBL16921603	0.75	SMN1; SMN2 (0.43)	SMN1; SMN2MAPTL3MBTL1POLBTDP1
	SCHEMBL752918	0.74	MAPT (0.43)	SMN1; SMN2MAPTL3MBTL1POLBTDP1
	SCHEMBL753257	0.74	SMN1; SMN2 (0.39)	SMN1; SMN2MAPTL3MBTL1POLBTDP1
	SCHEMBL751907	0.73	PTGER1 (0.40)	SMN1; SMN2MAPTL3MBTL1POLBTDP1
	SCHEMBL754426	0.73	KMT2A (0.43)	MAPTL3MBTL1POLBTDP1ALDH1A1
	SCHEMBL753517	0.73	KMT2A (0.42)	SMN1; SMN2POLBALDH1A1PTGER1KMT2A
	SCHEMBL755271	0.72	PTGER1 (0.38)	SMN1; SMN2MAPTL3MBTL1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.