SCHEMBL755271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL757246	0.87	POLB (0.38)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL16925405	0.84	FAAH (0.35)	MAPTPOLBTDP1ALDH1A1SMN1; SMN2
	SCHEMBL754426	0.81	KMT2A (0.43)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL752919	0.80	POLB (0.37)	MAPTPOLBTDP1ALDH1A1LMNA
	SCHEMBL752918	0.78	MAPT (0.43)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL751907	0.77	PTGER1 (0.40)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL16921603	0.77	SMN1; SMN2 (0.43)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL755776	0.77	THRA (0.47)	MAPTSMN1; SMN2THRATHRBLMNA
	SCHEMBL753158	0.77	PTGER1 (0.40)	PTGER1MAPTL3MBTL1POLBTDP1
	SCHEMBL16921609	0.77	LOXL2 (0.44)	PTGER1MAPTL3MBTL1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.