SCHEMBL754426

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16925481	0.86	MAPT (0.40)	KMT2AKDM4EGAAPTPN1ALDH1A1
	SCHEMBL755830	0.82	MAPT (0.43)	KMT2APOLBKDM4EALDH1A1MAPT
	SCHEMBL755271	0.81	PTGER1 (0.38)	KMT2APOLBALDH1A1MAPTPTGER1
	SCHEMBL752918	0.81	MAPT (0.43)	KMT2APOLBALDH1A1MAPTPTGER1
	SCHEMBL756396	0.81	LMNA (0.56)	KMT2APOLBKDM4EALDH1A1MAPT
	SCHEMBL757246	0.80	POLB (0.38)	POLBALDH1A1MAPTPTGER1LMNA
	SCHEMBL751907	0.80	PTGER1 (0.40)	KMT2APOLBKDM4EGAAALDH1A1
	SCHEMBL16921603	0.80	SMN1; SMN2 (0.43)	KMT2APOLBKDM4EGAAALDH1A1
	SCHEMBL753158	0.79	PTGER1 (0.40)	KMT2APOLBALDH1A1MAPTPTGER1
	SCHEMBL16921609	0.79	LOXL2 (0.44)	KMT2APOLBALDH1A1MAPTPTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.