SCHEMBL755377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15954354	0.73	MAPT (0.40)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL14848164	0.72	KDM4E (0.40)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL16644652	0.72	TSHR (0.40)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL757286	0.70	TSHR (0.46)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL19646278	0.69	ALDH1A1 (0.43)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL14829496	0.68	ALDH1A1 (0.48)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL12417943	0.66	TSHR (0.62)	KDM4EALDH1A1GAATSHRHSD17B10
	SCHEMBL25955239	0.66	EPHX2 (0.45)	ALDH1A1HPGDGAATSHRHSD17B10
	SCHEMBL17848969	0.66	KDM4E (0.47)	KDM4EALDH1A1HPGDGAAGLA
	SCHEMBL14846707	0.65	NOTUM (0.39)	KDM4EALDH1A1HPGDGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.