Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644656 | 0.86 | RARB (0.42) | TSHRRECQLTP53 | |
| SCHEMBL19646278 | 0.80 | ALDH1A1 (0.43) | TSHRTDP1L3MBTL1LMNAPOLB | |
| SCHEMBL15613740 | 0.77 | TSHR (0.53) | TSHRTDP1L3MBTL1LMNAPOLB | |
| SCHEMBL16748374 | 0.77 | BAZ2B (0.41) | TSHRTDP1L3MBTL1LMNAPOLB | |
| SCHEMBL16644651 | 0.75 | MAPT (0.46) | LMNAALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL755377 | 0.72 | KDM4E (0.40) | TSHRL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL27562479 | 0.71 | TSHR (0.47) | TSHRTDP1L3MBTL1LMNAKDM4E | |
| SCHEMBL15954354 | 0.71 | MAPT (0.40) | TSHRL3MBTL1LMNAKDM4EALDH1A1 | |
| SCHEMBL16640636 | 0.71 | TSHR (0.43) | TSHRTDP1L3MBTL1LMNAPOLB | |
| SCHEMBL31228728 | 0.70 | TSHR (0.49) | TSHRTDP1L3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9827336-B2 | Radio-pharmaceutical complexes | BAYER AS (NO) | 2017-11-28 | — | — | US | disclosed |
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-05-28 | — | — | US | disclosed |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2015-04-23 | — | — | US | disclosed |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | ALGETA ASA (NO) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147272-A1 | RADIO-PHARMACEUTICAL COMPLEXES | HCAR3, TYRO3, HCAR1 | TSHR 55/4885TDP1 981/4885L3MBTL1 4650/4885 |
| US-20150104385-A1 | RADIO-PHARMACEUTICAL COMPLEXES | CD22, HAVCR2, CD2 | TSHR 13/4885TDP1 940/4885L3MBTL1 3670/4885 |
| US-20150110817-A1 | RADIO-PHARMACEUTICAL COMPLEXES | TSPO, TK1, HCAR1 | TSHR 64/4885TDP1 308/4885L3MBTL1 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.