Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 3/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183364 | 0.70 | CTSB (0.35) | CTSLCTSKCTSBHTTJAK2 | |
| SCHEMBL4701045 | 0.68 | CTSK (0.45) | CTSLCTSKCTSBCTSS | |
| SCHEMBL6183366 | 0.66 | NPC1 (0.40) | PRKD1CTSKROCK2ROCK1CTSB | |
| SCHEMBL2694733 | 0.65 | SGK1 (0.51) | SGK1CAMKK2 | |
| SCHEMBL5528914 | 0.60 | ALDH1A1 (0.48) | CTSLHTT | |
| SCHEMBL21857189 | 0.59 | KDM4E (0.50) | ROCK2ROCK1JAK2 | |
| SCHEMBL5529215 | 0.59 | ALDH1A1 (0.49) | CTSLHTT | |
| SCHEMBL11038741 | 0.57 | KDM4E (0.53) | — | |
| SCHEMBL5522997 | 0.57 | SLC6A5 (0.48) | HTT | |
| SCHEMBL10912854 | 0.56 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161415-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055126-A2 | N-CYANOMETHYLAMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |