Acetic Acid

Acetic Acid

SCHEMBL755557

CC(=O)[O-].Nc1ccc2nc3ccc(N)cc3[s+]c2c1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A known ✓ P08913 1/20 0.38
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41
CSNK1A1 P48729 1/20 0.41
GSK3A P49840 1/20 0.41
LIMK1 P53667 1/20 0.41
IKBKE Q14164 1/20 0.41
MAPK14 Q16539 1/20 0.41
TAOK1 Q7L7X3 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
LMNA P02545 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HTT P42858 2/20 0.38
F2 P00734 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL755555 0.90 NQO2 (0.42) CHEK1AURKADAPK3CSNK1A1GSK3A
SCHEMBL146313 0.85 KMT2A (0.50) LMNAMEN1KMT2AHTTF2
SCHEMBL30165715 0.85 KMT2A (0.50) LMNAMEN1KMT2AHTTF2
Iodide SCHEMBL11279046 0.83 KMT2A (0.48) LMNAMEN1KMT2AHTTF2
Hydrochloric Acid SCHEMBL40555 0.83 MAPT (0.50) LMNAMEN1KMT2AHTTF2
SCHEMBL11281816 0.82 ALDH1A1 (0.44) LMNAMEN1KMT2AHTTF2
SCHEMBL12620639 0.79 KDM4E (0.43) LMNAMEN1KMT2AHTTF2
SCHEMBL12273001 0.77 HTR3A (0.48) LMNAMEN1KMT2AHTTF2
Iodide SCHEMBL12813166 0.75 HTR3A (0.47) LMNAMEN1KMT2AHTTF2
SCHEMBL31621939 0.75 APAF1 (0.47) LMNAMEN1KMT2AHTTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12006220-B2 Large scale production of oxidized graphene NANOXPLORE INC. (CA) 2024-06-11 US claimed
EP-3230386-B1 LARGE SCALE PRODUCTION OF OXIDIZED GRAPHENE NANOXPLORE INC (CA) 2024-02-21 EP claimed
EP-2450026-B1 DENTAL COMPOSITION HAVING A REDOX INDICATOR AND METHOD OF USING SAME KERR CORP (US) 2023-03-15 EP claimed
US-20230062310-A1 LARGE SCALE PRODUCTION OF OXIDIZED GRAPHENE NANOXPLORE INC. (CA) 2023-03-02 US claimed
EP-2450027-B1 DENTAL COMPOSITIONS HAVING SPECIAL FUNCTIONALITY AND TRI-BARREL PACKAGING KERR CORP (US) 2023-01-11 EP claimed
US-20220273813-A1 PHOTOSENSITIZER-CONJUGATED ANTIMICROBIAL CELLULOSE NANOCRYSTALS AND METHODS OF SYNTHESIZING AND USING SAME HNU MATERIALS INC. (CA) 2022-09-01 US claimed
EP-4021514-A1 PHOTOSENSITIZER-CONJUGATED ANTIMICROBIAL CELLULOSE NANOCRYSTALS AND METHODS OF SYNTHESIZING AND USING SAME HNU Materials Inc. (CA) 2022-07-06 EP claimed
WO-2021035349-A1 PHOTOSENSITIZER-CONJUGATED ANTIMICROBIAL CELLULOSE NANOCRYSTALS AND METHODS OF SYNTHESIZING AND USING SAME HEYNE BELINDA (CA) 2021-03-04 WO claimed
US-10322935-B2 Large scale production of thinned graphite, graphene, and graphite-graphene composites NANOXPLORE INC. (CA) 2019-06-18 US claimed
US-9950483-B2 Method for determining the surface concentration of carboxyl groups on a lens NOVARTIS AG (CH) 2018-04-24 US claimed
US-20090311484-A1 Molecular Resist Compositions, Methods of Patterning Substrates Using the Compositions and Process Products Prepared Therefrom NANO TERRA INC. (US) 2009-12-17 US claimed
WO-2009137049-A1 MOLECULAR RESIST COMPOSITIONS, METHODS OF PATTERNING SUBSTRATES USING THE COMPOSITIONS AND PROCESS PRODUCTS PREPARED THEREFROM NANO TERRA INC. (US) 2009-11-12 WO claimed
CN-101149383-A Device for detecting avian influenza virus antibody and detection method UNIV ZHEJIANG GONGSHANG (CN) 2008-03-26 CN claimed
CN-101149384-A Device for detecting avian influenza virus antigen and detection method UNIV ZHEJIANG GONGSHANG (CN) 2008-03-26 CN claimed
US-6946173-B2 Catheter balloon formed of ePTFE and a diene polymer ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2005-09-20 US claimed
JP-2005520639-A 2005-07-14 JP claimed
EP-1485142-A1 CATHETER BALLOON FORMED OF EPTFE AND A DIENE POLYMER Advanced Cardiovascular Systems, Inc. (US) 2004-12-15 EP claimed
WO-2003080145-A1 CATHETER BALLOON FORMED OF ePTFE AND A DIENE POLYMER ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2003-10-02 WO claimed
US-20030180488-A1 Catheter balloon formed of ePTFE and a diene polymer ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2003-09-25 US claimed
US-6348355-B1 STORAGE STABLE, OXIDATION RESISTANT REDOX INDICATOR COMPRISING PHENYLENEDIAMINE, INDOPHENOL, OR BENZIDINE DERIVATIVE; DETERMINATION OF OXIDIZABLE GASES OR VAPORS DRäGER SICHERHEITSTECHNIK GMBH (DE) 2002-02-19 US claimed