Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26241765 | 0.92 | MAOB (0.59) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5974513 | 0.90 | MAOB (0.68) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15568678 | 0.87 | MAOB (0.60) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4315663 | 0.85 | MAOB (0.62) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19732841 | 0.85 | PARP1 (0.59) | KMT2A | |
| SCHEMBL1436064 | 0.85 | KMT2A (0.76) | MAOBMAOAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1572959 | 0.85 | KMT2A (0.71) | KMT2ARAB9A | |
| SCHEMBL26999500 | 0.84 | LOXL2 (0.58) | KMT2ASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL28762521 | 0.84 | KMT2A (0.56) | KMT2A | |
| Hydrochloric Acid SCHEMBL25378558 | 0.83 | KMT2A (0.69) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2016-12-08 | — | — | US | claimed |
| EP-2033662-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2012-10-17 | — | — | EP | claimed |
| EP-2368579-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2011-09-28 | — | — | EP | claimed |
| US-20100009917-A1 | Modulating Enzymatic Processes by Addition of Diolcontaining Substances | NOVO NORDISK HEALTH CARE AG (CH) | 2010-01-14 | — | — | US | claimed |
| EP-2121952-A1 | MODULATING ENZYMATIC PROCESSES BY ADDITION OF DIOLCONTAINING SUBSTANCES | Novo Nordisk Health Care AG (CH) | 2009-11-25 | — | — | EP | claimed |
| US-20090264366-A1 | Transglutaminase Mediated Conjugation of Peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2009-10-22 | — | — | US | claimed |
| EP-2033662-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2009-03-11 | — | — | EP | claimed |
| WO-2008101957-A1 | MODULATING ENZYMATIC PROCESSES BY ADDITION OF DIOLCONTAINING SUBSTANCES | NOVO NORDISK HEALTH CARE AG (DK) | 2008-08-28 | — | — | WO | claimed |
| JP-2007518747-A | — | — | 2007-07-12 | — | — | JP | claimed |
| US-20070105770-A1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | claimed |
| EP-1708755-A2 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-10-11 | — | — | EP | claimed |
| WO-2005070468-A2 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-08-04 | — | — | WO | claimed |
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
| EP-2842576-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2016-12-08 | — | — | US | disclosed |
| EP-2842576-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2015-03-04 | — | — | EP | disclosed |
| WO-2008101957-A1 | MODULATING ENZYMATIC PROCESSES BY ADDITION OF DIOLCONTAINING SUBSTANCES | NOVO NORDISK HEALTH CARE AG (DK) | 2008-08-28 | — | — | WO | disclosed |
| US-20070105770-A1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | disclosed |
| EP-1708755-A2 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005070468-A2 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264366-A1 | Transglutaminase Mediated Conjugation of Peptides | TGM2, TGM3, TGM1 | MAOB 1309/4885MAOA 1196/4885KMT2A 2163/4885 |
| US-20100009917-A1 | Modulating Enzymatic Processes by Addition of Diolcontaining Substances | HSD17B14, CES2, PNLIP | MAOB 87/4885MAOA 105/4885KMT2A 3612/4885 |
| US-20070105770-A1 | Transglutaminase mediated conjugation of peptides | TGM2, TGM3, TGM1 | MAOB 1309/4885MAOA 1196/4885KMT2A 2163/4885 |
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | MAOB 1091/4885MAOA 2199/4885KMT2A 4556/4885 |
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | TGM2, TGM3, TGM1 | MAOB 1309/4885MAOA 1196/4885KMT2A 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.