Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593511 | 0.93 | CTRC (0.36) | P2RX3KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL7517108 | 0.91 | MEN1 (0.38) | KMT2AMEN1POLBLMNADHODH | |
| SCHEMBL7554427 | 0.80 | RAPGEF4 (0.46) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL7523160 | 0.77 | MAPT (0.37) | P2RX3KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL7517549 | 0.77 | P2RX3 (0.38) | P2RX3KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL7515289 | 0.75 | MAPT (0.45) | KMT2AMEN1MAPTPOLBLMNA | |
| SCHEMBL7522460 | 0.74 | MAPT (0.42) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7522665 | 0.70 | CTRC (0.39) | P2RX3KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL7560746 | 0.70 | KDM4E (0.46) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL7523106 | 0.67 | MEN1 (0.38) | KMT2AMEN1MAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |