Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | UNG | P13051 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523106 | 0.91 | MEN1 (0.38) | MAPTMAPK1KMT2APOLBMEN1 | |
| SCHEMBL7517549 | 0.77 | P2RX3 (0.38) | MAPTMAPK1P2RX3KMT2ALMNA | |
| SCHEMBL7558368 | 0.77 | P2RX3 (0.38) | MAPTMAPK1P2RX3KMT2ALMNA | |
| SCHEMBL7519427 | 0.74 | GRM4 (0.44) | KMT2AMEN1 | |
| SCHEMBL7593511 | 0.70 | CTRC (0.36) | MAPTMAPK1P2RX3KMT2ALMNA | |
| SCHEMBL7522665 | 0.70 | CTRC (0.39) | MAPTMAPK1P2RX3KMT2APOLB | |
| SCHEMBL7554903 | 0.69 | RAB9A (0.42) | MAPTP2RX3KMT2ALMNAHTT | |
| SCHEMBL7517906 | 0.67 | KMT2A (0.38) | MAPTKMT2APOLBMEN1PKM | |
| SCHEMBL7517108 | 0.67 | MEN1 (0.38) | KMT2ALMNAPOLBMEN1IDO1 | |
| SCHEMBL7524850 | 0.66 | IDO1 (0.47) | KMT2ALMNAMEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |