Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522665 | 0.93 | CTRC (0.39) | P2RX3KMT2APKML3MBTL1MEN1 | |
| SCHEMBL7517906 | 0.91 | KMT2A (0.38) | KMT2APKML3MBTL1MEN1MAPT | |
| SCHEMBL29926760 | 0.81 | RAB9A (0.40) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL28463421 | 0.81 | RAB9A (0.40) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7524238 | 0.80 | RAPGEF4 (0.46) | KMT2APKML3MBTL1MEN1MAPT | |
| SCHEMBL7523160 | 0.77 | MAPT (0.37) | P2RX3KMT2APKML3MBTL1MEN1 | |
| SCHEMBL7558368 | 0.77 | P2RX3 (0.38) | P2RX3KMT2APKML3MBTL1MEN1 | |
| SCHEMBL7518027 | 0.75 | RAB9A (0.45) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL7524987 | 0.74 | PPIA (0.46) | KMT2APKMMEN1MAPTPOLB | |
| SCHEMBL7524917 | 0.74 | ULK1 (0.39) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |