Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 10/20 | 0.50 |
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | RARA | P10276 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623373 | 0.94 | ALDH1A1 (0.63) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL901113 | 0.84 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL901112 | 0.84 | ALDH1A1 (0.68) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL2554589 | 0.83 | ALDH1A1 (1.00) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL3218915 | 0.83 | AKR1C3 (0.67) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| Terephthalic Acid SCHEMBL27501159 | 0.80 | TSHR (0.67) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL2464948 | 0.80 | ESR1 (0.46) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL319810 | 0.79 | ALDH1A1 (0.61) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL319809 | 0.79 | ALDH1A1 (0.61) | ALDH1A1POLBTDP1GLAL3MBTL1 | |
| SCHEMBL10529261 | 0.79 | NR4A1 (0.56) | ALDH1A1POLBTDP1GLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | claimed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | claimed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | claimed |
| US-20240043281-A1 | TITANIUM ZIRCONIUM OXIDE NANOPARTICLES, PHOTORESIST AND PATTERNING METHOD THEREFOR, AND METHOD FOR GENERATING PRINTED CIRCUIT BOARD | BEIJING VFORTUNE NEW ENERGY POWER TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-02-08 | — | — | US | disclosed |
| WO-2022121888-A1 | TITANIUM ZIRCONIUM OXIDE NANOPARTICLES, PHOTORESIST AND PATTERNING METHOD THEREFOR, AND METHOD FOR GENERATING PRINTED CIRCUIT BOARD | 清华大学 | 2022-06-16 | — | — | WO | disclosed |
| WO-2022033366-A1 | PHOTORESIST COMPOSITION, METHOD FOR USING SAME TO FORM LITHOGRAPHIC PATTERN, AND USES OF SAME | 无锡华睿芯材科技有限公司 | 2022-02-17 | — | — | WO | disclosed |
| WO-2022033367-A1 | PHOTORESIST, METHOD FOR PATTERNING PHOTORESIST, AND METHOD FOR ETCHING INTEGRATED CIRCUIT BOARD | 无锡华睿芯材科技有限公司 | 2022-02-17 | — | — | WO | disclosed |
| WO-2021259092-A1 | PHOTORESIST COMPOSITION AND METHOD FOR FORMING THIN FILM PATTERN AND ARRAY SUBSTRATE BY USING SAME | 无锡华睿芯材科技有限公司 | 2021-12-30 | — | — | WO | disclosed |
| CN-111704723-B | Composition, zirconium-based metal crosslinked polymeric network, separator and preparation method thereof, and electrochemical cell | 清华大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-111704723-A | Composition, zirconium-based metal crosslinked polymeric network, separator and preparation method thereof, and electrochemical cell | 清华大学 | 2020-09-25 | — | — | CN | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20090215814-A1 | Method of inhibiting neurotrophin-receptor binding | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-08-27 | — | — | US | disclosed |
| US-20080113961-A1 | Immunosuppressants with low toxicity; 1-({4-Methyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl}methyl)azetidine-3-carboxylic acid for example; autoimmune diseases and transplant rejection; N-substituted azetidine, pyrrolidine or piperidine compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-05-15 | — | — | US | disclosed |
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-5166405-A | Polymers suitable for use as positive photoresists | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5106932-A | Polymers usable as positive photoresists | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-4883916-A | ANTICHOLESTEROL, ANTIARTERIOSCELEROSIS | EISAI CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4788330-A | Polyprenyl compounds | EISAI CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0194693-A1 | Polyprenyl compounds, processes for preparing them, and pharmaceutical composition containing them | Eisai Co., Ltd. (JP) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215814-A1 | Method of inhibiting neurotrophin-receptor binding | NGF, NTRK2, BDNF | ALDH1A1 2096/4885POLB 2851/4885TDP1 1843/4885 |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | ALDH1A1 687/4885POLB 671/4885TDP1 3843/4885 |
| US-20080113961-A1 | Immunosuppressants with low toxicity; 1-({4-Methyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl}methyl)azetidine-3-carboxylic acid for example; autoimmune diseases and transplant rejection; N-substituted azetidine, pyrrolidine or piperidine compounds | TPMT, AZI2, IDO1 | ALDH1A1 81/4885POLB 4377/4885TDP1 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.