Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650786 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| Potassium Ion SCHEMBL9650212 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9650225 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL1775446 | 0.80 | ALOX15 (0.48) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL27074412 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL2495592 | 0.79 | KDR (0.53) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7562987 | 0.78 | AR (0.42) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL16569634 | 0.77 | ALDH1A1 (0.48) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL2661752 | 0.76 | XDH (0.49) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL1277858 | 0.76 | RAB9A (0.52) | ALDH1A1POLBKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |