Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650225 | 0.98 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| Potassium Ion SCHEMBL9650212 | 0.98 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL1775446 | 0.85 | ALOX15 (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL27074412 | 0.85 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL7559710 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL2661752 | 0.78 | XDH (0.49) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL28844710 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL18332147 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL1277858 | 0.77 | RAB9A (0.52) | ALDH1A1LMNAHPGDSMN1; SMN2POLB | |
| SCHEMBL13684585 | 0.76 | CDK1 (0.50) | ALDH1A1LMNAHPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517225-A1 | Aminopyrrolidine platinum compounds, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1992-12-09 | — | — | EP | disclosed |