SCHEMBL755973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753011	0.89	JAK2 (0.45)	LIPGGRM5JAK2JAK3GRM3
	SCHEMBL754565	0.87	LIPG (0.35)	LIPGALDH1A1HPGDHTT
	SCHEMBL752783	0.86	ACACB (0.38)	PKMGRM5HTR1AHTR7PTGER1
	SCHEMBL754930	0.85	GPR84 (0.38)	LIPGALDH1A1
	SCHEMBL752750	0.84	NPC1 (0.50)	LIPGALDH1A1MAPK1
	SCHEMBL754125	0.83	LIPG (0.33)	LIPG
	SCHEMBL752280	0.81	LIPG (0.45)	LIPGALDH1A1TSHR
	SCHEMBL756220	0.78	JAK2 (0.43)	LIPGGRM5JAK2JAK3GRM3
	SCHEMBL755667	0.77	ALKBH1 (0.43)	PKMLIPGGRM5PTGER1HRH4
	SCHEMBL751416	0.77	JAK2 (0.44)	LIPGGRM5JAK2JAK3GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.