Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL756009

COc1ccc([S+](c2ccccc2)c2ccccc2)cc1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
KMT2A Q03164 2/20 0.40
GAA P10253 2/20 0.40
CA4 P22748 1/20 0.39
HSD11B1 P28845 2/20 0.39
LTA4H P09960 1/20 0.39
HTT P42858 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
EDNRA P25101 2/20 0.38
PKM P14618 1/20 0.38
EDNRB P24530 1/20 0.38
PPARG P37231 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ACP3 P15309 1/20 0.37
BACE1 P56817 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL36492 0.88 KCNH2 (0.46) KMT2AGAACA4HSD11B1LTA4H
Trifluoromethanesulfonic Acid SCHEMBL3143626 0.88 KCNH2 (0.46) KMT2AGAACA4HSD11B1LTA4H
SCHEMBL6869805 0.85 GAA (0.44) KMT2AGAACA4HTTNFE2L2
Trifluoromethanesulfonic Acid SCHEMBL3964223 0.85 PPARA (0.34) KMT2AHSD11B1PPARGNFE2L2
Trifluoromethanesulfonic Acid SCHEMBL8497201 0.85 HSD11B1 (0.40) KMT2AGAAHSD11B1PKMALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL5619591 0.85 PPARA (0.34) KMT2AHSD11B1PPARGNFE2L2
Anisole SCHEMBL4551224 0.85 CA4 (0.56) CES2CES1KMT2AGAACA4
Trifluoromethanesulfonic Acid SCHEMBL759937 0.85 PTPN1 (0.41) CES1HSD11B1ALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL2324715 0.82 KCNH2 (0.43) KMT2AGAAHTTNPC1RAB9A
SCHEMBL6869627 0.82 GAA (0.42) KMT2AGAAHSD11B1HTTNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302015-B1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT JNC CORP (JP) 2016-10-05 EP disclosed
EP-2360229-B1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC CORP (JP) 2016-08-31 EP disclosed
US-8586803-B2 Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2013-11-19 US disclosed
US-8586153-B2 Chlorofluorobenzene compound, optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2013-11-19 US disclosed
US-20130289316-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2013-10-31 US disclosed
US-8501285-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2013-08-06 US disclosed
US-8475887-B2 Optically isotropic liquid crystal medium, and optical device JNC CORPORATION (JP) 2013-07-02 US disclosed
US-20130088658-A1 CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE HASEBA YASUHIRO (JP) 2013-04-11 US disclosed
US-20130085306-A1 CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE HASEBA YASUHIRO (JP) 2013-04-04 US disclosed
US-8409673-B2 Chlorobenzene derivative, optically isotropic liquid crystal medium, and optical device JNC CORPORATION (JP) 2013-04-02 US disclosed
EP-2433923-A1 CHLOROBENZENE DERIVATIVE, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL ELEMENT JNC Corporation (JP) 2012-03-28 EP disclosed
EP-2098583-B1 Optically isotropic liquid crystal medium and optical device JNC CORP (JP) 2012-03-21 EP disclosed
US-20110242473-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORPORATION (JP) 2011-10-06 US disclosed
EP-2360229-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC Corporation (JP) 2011-08-24 EP disclosed
EP-2302015-A1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT Chisso Corporation (JP) 2011-03-30 EP disclosed
US-20110069245-A1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT CHISSO PETROCHEMICAL CORPORATION (JP) 2011-03-24 US disclosed
US-20100296029-A1 CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2010-11-25 US disclosed
US-7722783-B2 Optically isotropic liquid crystal medium and optical device CHISSO CORPORATION (JP) 2010-05-25 US disclosed
EP-2098583-A2 Optically isotropic liquid crystal medium and optical device Chisso Corporation (JP) 2009-09-09 EP disclosed
US-20090135368-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE CHISSO CORPORATION (JP) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130085306-A1 CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE DDT, BRAF, CFAP410 CES2 1734/4885CES1 3484/4885KMT2A 3429/4885
US-20100296029-A1 CHLOROFLUOROBENZENE COMPOUND, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL DEVICE DDT, BRAF, LEF1 CES2 1497/4885CES1 3390/4885KMT2A 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.