Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004236 | 0.88 | MMP2 (0.43) | CRHBPCRHR2PPARGMMP2MAPT | |
| SCHEMBL7007295 | 0.80 | PTPN11 (0.37) | CRHBPCRHR2MAPTGAAALDH1A1 | |
| SCHEMBL7556080 | 0.80 | CRHBP (0.43) | CRHBPCRHR2MMP2MAPTPTGER1 | |
| SCHEMBL7003191 | 0.79 | HPGD (0.41) | MAPTALDH1A1PTGER1LMNAHPGD | |
| SCHEMBL7003666 | 0.78 | PPARG (0.41) | PPARGMMP2MAPTGAAALDH1A1 | |
| SCHEMBL7007699 | 0.77 | CRHBP (0.39) | CRHBPCRHR2MAPTGAAALDH1A1 | |
| SCHEMBL7002021 | 0.73 | NR1H4 (0.33) | PPARGALDH1A1MCL1TDP1L3MBTL1 | |
| SCHEMBL7561375 | 0.71 | TDP1 (0.42) | CRHBPCRHR2MAPTGAAALDH1A1 | |
| SCHEMBL7006171 | 0.68 | ESR1 (0.34) | GAAALDH1A1LMNAHPGDCYP2C9 | |
| SCHEMBL7004596 | 0.68 | PTGER1 (0.39) | PTGER1MCL1MRGPRX4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |