Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563170 | 0.91 | NPSR1 (0.45) | NPSR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7561017 | 0.86 | SMN1; SMN2 (0.45) | NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7561006 | 0.81 | SMN1; SMN2 (0.44) | NPSR1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7561384 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7564712 | 0.79 | TTR (0.48) | NPSR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7561981 | 0.78 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2CA1CA2ACHE | |
| SCHEMBL7570883 | 0.77 | LMNA (0.46) | NPSR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7567148 | 0.77 | NPC1 (0.38) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7562191 | 0.77 | TTR (0.48) | NPSR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7561001 | 0.73 | MMP13 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |