Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537898 | 0.94 | GPR27 (0.54) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL7537677 | 0.88 | KMT2A (0.59) | GPR27KMT2AMEN1MAPTIDH1 | |
| SCHEMBL7533623 | 0.80 | ACLY (0.55) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL7532812 | 0.79 | MAPT (0.47) | GPR27LMNAKMT2AMEN1MAPT | |
| SCHEMBL7534328 | 0.78 | NPC1 (0.56) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL7531361 | 0.77 | L3MBTL1 (0.53) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL7534321 | 0.76 | GPR27 (0.55) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL7561599 | 0.75 | MAPT (0.52) | GPR27LMNAPTBP1KMT2AMEN1 | |
| SCHEMBL3791521 | 0.72 | PGR (0.81) | KMT2AMEN1PGRCYP1A2CYP3A4 | |
| SCHEMBL7537162 | 0.72 | MAPT (0.57) | LMNAKMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |