Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381716 | 0.87 | KDM4E (0.54) | KDM4ENPC1RAB9AMEN1LMNA | |
| SCHEMBL9525322 | 0.79 | NPC1 (0.59) | KDM4ENPC1RAB9AMEN1LMNA | |
| SCHEMBL15775220 | 0.78 | KDM4E (0.58) | KDM4ENPC1RAB9AMEN1LMNA | |
| SCHEMBL4662798 | 0.78 | NPSR1 (0.52) | KDM4EMEN1LMNAKMT2AGAA | |
| SCHEMBL13647658 | 0.77 | GAA (0.60) | KDM4ENPC1RAB9AMEN1LMNA | |
| SCHEMBL1381718 | 0.76 | ALDH1A1 (0.53) | KDM4ENPC1RAB9AMEN1LMNA | |
| SCHEMBL4664426 | 0.75 | KDM4E (0.51) | KDM4ENPC1RAB9ATRPV1 | |
| SCHEMBL3919470 | 0.73 | RXFP1 (0.55) | KDM4EGAARXFP1PTGS1ALDH1A1 | |
| SCHEMBL24574896 | 0.70 | LMNA (0.69) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL7172821 | 0.68 | HPGD (0.53) | RAB9AMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265850-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070671-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |