Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381716 | 0.90 | KDM4E (0.54) | NPSR1RXFP1P2RX1KDM4ESMN1; SMN2 | |
| SCHEMBL7455132 | 0.81 | ALDH1A1 (0.54) | RXFP1P2RX1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL1843019 | 0.81 | ALDH1A1 (0.46) | NPSR1RXFP1KMT2AALDH1A1LMNA | |
| SCHEMBL1382114 | 0.81 | LMNA (0.54) | NPSR1LMNAGAA | |
| SCHEMBL4664426 | 0.80 | KDM4E (0.51) | KDM4E | |
| SCHEMBL7561932 | 0.78 | KDM4E (0.49) | RXFP1P2RX1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4663130 | 0.77 | PDE4B (0.46) | NPSR1RXFP1P2RX1KDM4EALDH1A1 | |
| SCHEMBL14263664 | 0.76 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4666449 | 0.74 | AURKA (0.48) | NPSR1P2RX1ALDH1A1TP53 | |
| SCHEMBL13761353 | 0.74 | CES2 (0.60) | NPSR1KDM4ESMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338978-B2 | Insecticidal anthranilamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | claimed |
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | claimed |
| US-20060079561-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2006-04-13 | — | — | US | claimed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | claimed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | claimed |
| CN-1419537-A | Insecticidal anthranilamides | DU PONT (US) | 2003-05-21 | — | — | CN | claimed |
| CN-1419537-B | Insecticidal anthranilamides | DU PONT | 2011-02-23 | — | — | CN | disclosed |
| EP-1700845-B1 | Insecticidal anthranilamides | DU PONT (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7338978-B2 | Insecticidal anthranilamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1265850-B1 | INSECTICIDAL ANTHRANILAMIDES | DU PONT (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1700845-A1 | Insecticidal anthranilamides | E.I.Du pont de nemours and company (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060079561-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2006-04-13 | — | — | US | disclosed |
| US-6995178-B2 | Insecticidal anthranilamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040142984-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2004-07-22 | — | — | US | disclosed |
| US-20040110777-A1 | Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-06-10 | — | — | US | disclosed |
| US-6747047-B2 | ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-20030229050-A1 | Insecticidal anthranilamides | FMC CORPORATION | 2003-12-11 | — | — | US | disclosed |
| CN-1419537-A | Insecticidal anthranilamides | DU PONT (US) | 2003-05-21 | — | — | CN | disclosed |
| EP-1265850-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070671-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110777-A1 | Quinazolinones and pyridinylpyrimidinones for controlling invertebrate pests | SYNJ1, SBK3, KCNK4 | NPSR1 1033/4885RXFP1 1926/4885P2RX1 547/4885 |
| US-20040142984-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, AKR7A2 | NPSR1 594/4885RXFP1 1008/4885P2RX1 1273/4885 |
| US-20060079561-A1 | Insecticidal anthranilamides | ANTXR2, CYB5R3, NIT2 | NPSR1 411/4885RXFP1 1401/4885P2RX1 791/4885 |
| US-20030229050-A1 | Insecticidal anthranilamides | ANTXR2, NIT2, CYB5R3 | NPSR1 445/4885RXFP1 1165/4885P2RX1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.