Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690365 | 0.87 | MAPT (0.59) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL7430964 | 0.81 | GPR35 (0.52) | GAAMAPTDDX3XKMT2AALDH1A1 | |
| SCHEMBL9564631 | 0.79 | ALDH1A1 (0.66) | GAAMAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL3185695 | 0.79 | KMT2A (0.66) | GAAMAPTGFERPEPDKMT2A | |
| SCHEMBL29521756 | 0.79 | DDX3X (0.74) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL5544315 | 0.79 | MAPT (0.52) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL33716 | 0.79 | DDX3X (0.74) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL8350546 | 0.78 | GAA (0.50) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL22699676 | 0.78 | MAPT (0.50) | GAAMAPTGFERDDX3XPEPD | |
| SCHEMBL5180715 | 0.78 | SIGMAR1 (0.57) | GAAMAPTGFERDDX3XPEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087851-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIMIDINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |