Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.62 |
| ▸ | PLAT | P00750 | 1/20 | 0.62 |
| ▸ | ACLY | P53396 | 1/20 | 0.59 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.56 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | IDH2 | P48735 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | USP8 | P40818 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572438 | 0.90 | SLC20A2 (0.63) | PLAUPLATSLC20A2SLC20A1NR3C1 | |
| SCHEMBL7568102 | 0.88 | PTPN2 (0.52) | PLAUPLATACLYSLC20A2SLC20A1 | |
| SCHEMBL7573002 | 0.88 | ACLY (0.59) | PLAUPLATACLYSLC20A2SLC20A1 | |
| SCHEMBL7566650 | 0.86 | ACLY (0.57) | PLAUPLATACLYNR3C1PGR | |
| SCHEMBL7578393 | 0.85 | SLC20A2 (0.64) | PLAUPLATSLC20A2SLC20A1NR3C1 | |
| SCHEMBL7596158 | 0.84 | ACLY (0.59) | PLAUPLATACLYNR3C1PGR | |
| SCHEMBL30110890 | 0.81 | ACLY (0.51) | PLAUPLATACLYSLC20A2SLC20A1 | |
| SCHEMBL6380677 | 0.80 | SLC20A2 (0.71) | PLAUPLATACLYSLC20A2SLC20A1 | |
| SCHEMBL7573750 | 0.79 | ACLY (0.56) | ACLYNR3C1PGRARESR2 | |
| SCHEMBL12201483 | 0.79 | SLC20A2 (0.72) | PLAUPLATACLYSLC20A2SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |