Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 2/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571744 | 0.88 | HSPD1 (0.52) | ACLYMEN1KMT2AGAAHSD17B2 | |
| SCHEMBL7592771 | 0.81 | MEN1 (0.74) | ACLYMEN1KMT2AGAAHSD17B2 | |
| SCHEMBL7570746 | 0.81 | MCL1 (0.64) | ACLYMEN1KMT2AGAAHSD17B2 | |
| SCHEMBL7567283 | 0.79 | PLAU (0.62) | ACLYMEN1KMT2AGAALMNA | |
| SCHEMBL7596158 | 0.79 | ACLY (0.59) | ACLYMEN1KMT2AGAAHSD17B2 | |
| SCHEMBL7567344 | 0.78 | ACLY (0.48) | ACLYMEN1KMT2AGAACKS1B | |
| SCHEMBL7566442 | 0.78 | ACLY (0.48) | ACLYMEN1KMT2AGAACKS1B | |
| SCHEMBL7571635 | 0.78 | FFAR1 (0.66) | MEN1KMT2AGAAHSD17B2LMNA | |
| SCHEMBL10583133 | 0.78 | HSD17B2 (0.58) | ACLYMEN1KMT2AGAAHSD17B2 | |
| SCHEMBL7567262 | 0.78 | CCR2 (0.55) | ACLYMEN1KMT2AGAACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |