Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.71 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ACLY | P53396 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | USP8 | P40818 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | IDH2 | P48735 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201483 | 0.90 | SLC20A2 (0.72) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL7572438 | 0.86 | SLC20A2 (0.63) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL23141255 | 0.85 | KDM1A (0.74) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL7128814 | 0.83 | SLC20A2 (1.00) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL3985583 | 0.82 | METAP2 (0.72) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL7454156 | 0.80 | MEN1 (0.72) | SLC20A2SLC20A1MEN1KMT2A | |
| SCHEMBL7567283 | 0.80 | PLAU (0.62) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL23141186 | 0.80 | KDM1A (0.81) | MEN1GAAKMT2AACLYKDM1A | |
| SCHEMBL7569668 | 0.79 | KMT2A (0.76) | SLC20A2SLC20A1MEN1GAAKMT2A | |
| SCHEMBL23200342 | 0.77 | MEN1 (0.66) | MEN1GAAKMT2APGRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332608-B2 | Anthranilamides and methods of their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-19 | — | — | US | disclosed |
| US-7332608-B2 | Anthranilamides and methods of their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-19 | — | — | US | disclosed |
| US-7235690-B2 | Anthranilamides and methods of their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-7235690-B2 | Anthranilamides and methods of their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| WO-2005113490-A1 | SULFONE-CONTAINING PRODRUGS | ICAGEN, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050267032-A1 | Sulfone-containing prodrugs | ICAGEN, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267032-A1 | Sulfone-containing prodrugs | KCNQ5, KCNE1, KCNH2 | SLC20A2 48/4885SLC20A1 40/4885MEN1 2143/4885 |
| US-20070117807-A1 | ANTHRANILAMIDES AND METHODS OF THEIR USE | KCNH1, KCNH2, KCNJ2 | SLC20A2 3088/4885SLC20A1 2731/4885MEN1 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.